sa26_AGTR1_cytoplasm -> ACE2_AGTR1_complex angiotensin_II_simple_molecule_cytoplasm -| ACE2_AGTR1_complex sa30_ACE2_cytoplasm -> ACE2_Spike_complex_complex S -> ACE2_Spike_complex_complex Camostat_mesilate_drug -| ACE2_Spike_complex_complex TMPRSS2 -> ACE2_Spike_complex_complex sa140_AGTR1_cytoplasm -> MAS1_AGTR1_complex AGT -> angiotensin_I_simple_molecule REN -> angiotensin_I_simple_molecule angiotensin_1_12_simple_molecule -> angiotensin_I_simple_molecule sa29_ACE_cytoplasm -> angiotensin_I_simple_molecule CTSD -> angiotensin_I_simple_molecule CTSG -> angiotensin_I_simple_molecule angiotensin_I_simple_molecule -> angiotensin_1_9_simple_molecule sa30_ACE2_cytoplasm -> angiotensin_1_9_simple_molecule angiotensin_I_simple_molecule -> angiotensin_II_simple_molecule_cytoplasm sa29_ACE_cytoplasm -> angiotensin_II_simple_molecule_cytoplasm S -> angiotensin_II_simple_molecule_cytoplasm angiotensin_1_12_simple_molecule -> angiotensin_II_simple_molecule_cytoplasm CMA1 -> angiotensin_II_simple_molecule_cytoplasm KLK1 -> angiotensin_II_simple_molecule_cytoplasm angiotensin_1_9_simple_molecule -> angiotensin_1_7_simple_molecule_cytoplasm sa100_ACE_cytoplasm -> angiotensin_1_7_simple_molecule_cytoplasm sa39_MME_cytoplasm -> angiotensin_1_7_simple_molecule_cytoplasm angiotensin_II_simple_molecule_cytoplasm -> angiotensin_1_7_simple_molecule_cytoplasm sa30_ACE2_cytoplasm -> angiotensin_1_7_simple_molecule_cytoplasm PRCP -> angiotensin_1_7_simple_molecule_cytoplasm angiotensin_I_simple_molecule -> angiotensin_1_7_simple_molecule_cytoplasm angiotensin_1_12_simple_molecule -> angiotensin_1_7_simple_molecule_cytoplasm THOP1 -> angiotensin_1_7_simple_molecule_cytoplasm PREP -> angiotensin_1_7_simple_molecule_cytoplasm sa79_AGTR2_cytoplasm -> sa25_AGTR2_cytoplasm CGP42112A_drug -> sa25_AGTR2_cytoplasm angiotensin_II_simple_molecule_cytoplasm -> sa25_AGTR2_cytoplasm angiotensin_A_simple_molecule -> sa25_AGTR2_cytoplasm angiotensin_1_7_simple_molecule_cytoplasm -> sa25_AGTR2_cytoplasm angiotensin_1_9_simple_molecule -> sa25_AGTR2_cytoplasm sa77_MAS1_cytoplasm -> sa27_MAS1_cytoplasm angiotensin_1_5_simple_molecule -> sa27_MAS1_cytoplasm AR234960_drug -> sa27_MAS1_cytoplasm angiotensin_1_7_simple_molecule_cytoplasm -> sa27_MAS1_cytoplasm sa200_estradiol_simple_molecule_cytoplasm -> sa29_ACE_cytoplasm Calcitriol_simple_molecule_cell -| sa29_ACE_cytoplasm ACE2_gene -> sa30_ACE2_cytoplasm sa169_estradiol_simple_molecule_cytoplasm -> sa30_ACE2_cytoplasm S -| sa30_ACE2_cytoplasm Calcitriol_simple_molecule_cytoplasm -> sa30_ACE2_cytoplasm SARS_CoV_2_infection_phenotype -| sa30_ACE2_cytoplasm aging_phenotype -> sa30_ACE2_cytoplasm hypertension_phenotype -| sa30_ACE2_cytoplasm _Diabetes_mellitus__type_II_phenotype -| sa30_ACE2_cytoplasm angiotensin_1_7_simple_molecule_cytoplasm -> angiotensin_1_5_simple_molecule sa100_ACE_cytoplasm -> angiotensin_1_5_simple_molecule ethynylestradiol_simple_molecule -> AGT androgen_simple_molecule -> TMPRSS2 angiotensin_1_7_simple_molecule_cytoplasm -> alamandine_simple_molecule angiotensin_A_simple_molecule -> alamandine_simple_molecule sa30_ACE2_cytoplasm -> alamandine_simple_molecule sa94_MRGPRD_cytoplasm -> sa50_MRGPRD_cytoplasm alamandine_simple_molecule -> sa50_MRGPRD_cytoplasm angiotensin_1_7_simple_molecule_cytoplasm -> sa50_MRGPRD_cytoplasm angiotensin_II_simple_molecule_cytoplasm -> angiotensin_A_simple_molecule sa25_AGTR2_cytoplasm -> vasoconstriction_phenotype sa27_MAS1_cytoplasm -> vasoconstriction_phenotype sa156_LNPEP_cytoplasm -> vasoconstriction_phenotype sa50_MRGPRD_cytoplasm -> vasoconstriction_phenotype sa102_AGTR1_cytoplasm -> vasoconstriction_phenotype sa50_MRGPRD_cytoplasm -> inflammatory_response_phenotype sa27_MAS1_cytoplasm -> inflammatory_response_phenotype sa156_LNPEP_cytoplasm -> inflammatory_response_phenotype sa102_AGTR1_cytoplasm -> inflammatory_response_phenotype angiotensin_II_simple_molecule_cytoplasm -> angiotensin_III_simple_molecule sa64_ENPEP_cytoplasm -> angiotensin_III_simple_molecule angiotensin_III_simple_molecule -> angiotensin_IV_simple_molecule ANPEP_ -> angiotensin_IV_simple_molecule sa162_ENPEP_cytoplasm -> sa64_ENPEP_cytoplasm QGC001_drug -| sa64_ENPEP_cytoplasm sa193_sex__male_phenotype_default_compartment -| sa64_ENPEP_cytoplasm Calcitriol_simple_molecule_cell -| REN sa30_ACE2_cytoplasm -> ACE2__soluble ADAM17 -> ACE2__soluble sa167_AGTR1_cytoplasm -> ACE2__soluble aldosterone_simple_molecule -| sa77_MAS1_cytoplasm SARS_CoV_2_infection_phenotype -> angiotensin_II_simple_molecule_default_compartment angiotensin_II_simple_molecule_default_compartment -> angiotensin_1_7_simple_molecule_default_compartment ACE2__soluble -> angiotensin_1_7_simple_molecule_default_compartment sa30_ACE2_cytoplasm -> sa98_ACE2_cytoplasm sa44_sex__male_phenotype_default_compartment -> sa98_ACE2_cytoplasm aging_phenotype -> sa98_ACE2_cytoplasm hypertension_phenotype -> sa98_ACE2_cytoplasm sa28_ACE_cytoplasm -> sa100_ACE_cytoplasm aging_phenotype -| sa100_ACE_cytoplasm sa44_sex__male_phenotype_default_compartment -| sa100_ACE_cytoplasm aldosterone_simple_molecule -> sa100_ACE_cytoplasm hypertension_phenotype -> sa100_ACE_cytoplasm sa26_AGTR1_cytoplasm -> sa102_AGTR1_cytoplasm angiotensin_II_simple_molecule_cytoplasm -> sa102_AGTR1_cytoplasm angiotensin_IV_simple_molecule -> sa102_AGTR1_cytoplasm angiotensin_A_simple_molecule -> sa102_AGTR1_cytoplasm Losartan_drug -| sa102_AGTR1_cytoplasm angiotensin_1_7_simple_molecule_cytoplasm -| sa102_AGTR1_cytoplasm angiotensin_1_12_simple_molecule -> angiotensin_1_4_simple_molecule sa39_MME_cytoplasm -> angiotensin_1_4_simple_molecule MAS1_AGTR1_complex -| sa140_AGTR1_cytoplasm angiotensin_II_simple_molecule_cytoplasm -> sa140_AGTR1_cytoplasm sa29_ACE_cytoplasm -> sa146_ACE_cytoplasm Lisinopril_drug -| sa146_ACE_cytoplasm ABO_blood_group_system_phenotype -> sa146_ACE_cytoplasm sa152_LNPEP_cytoplasm -> sa156_LNPEP_cytoplasm angiotensin_IV_simple_molecule -> sa156_LNPEP_cytoplasm angiotensin_3_7_simple_molecule -> sa156_LNPEP_cytoplasm sa27_MAS1_cytoplasm -> oxidative_stress_phenotype sa102_AGTR1_cytoplasm -> oxidative_stress_phenotype angiotensin_1_7_simple_molecule_cytoplasm -> angiotensin_3_7_simple_molecule angiotensin_II_simple_molecule_cytoplasm -> angiotensin_3_7_simple_molecule angiotensin_IV_simple_molecule -> angiotensin_3_7_simple_molecule ACE2_Spike_complex_complex -> viral_replication_cycle_phenotype sa27_MAS1_cytoplasm -> fibrosis_phenotype sa25_AGTR2_cytoplasm -> fibrosis_phenotype sa102_AGTR1_cytoplasm -> fibrosis_phenotype sa27_MAS1_cytoplasm -> thrombosis_phenotype sa102_AGTR1_cytoplasm -> thrombosis_phenotype sa156_LNPEP_cytoplasm -> neurodegeneration_phenotype sa39_MME_cytoplasm -> sa194_MME_cytoplasm sa44_sex__male_phenotype_default_compartment -> sa194_MME_cytoplasm sa204_AGTR1_cytoplasm -> aldosterone_simple_molecule sa102_AGTR1_cytoplasm -> cognition_phenotype sa156_LNPEP_cytoplasm -> cognition_phenotype sa102_AGTR1_cytoplasm -> pulmonary_edema_phenotype sa102_AGTR1_cytoplasm -> platelet_aggregation_phenotype $ACE2_AGTR1_complex: (sa26_AGTR1_cytoplasm & !angiotensin_II_simple_molecule_cytoplasm) $ACE2_Spike_complex_complex: ((sa30_ACE2_cytoplasm & S) | ((S & TMPRSS2) & !Camostat_mesilate_drug)) $ACE2__soluble: ((ADAM17 | sa167_AGTR1_cytoplasm) & sa30_ACE2_cytoplasm) $AGT: ethynylestradiol_simple_molecule $MAS1_AGTR1_complex: sa140_AGTR1_cytoplasm $REN: !Calcitriol_simple_molecule_cell $TMPRSS2: androgen_simple_molecule $alamandine_simple_molecule: (angiotensin_1_7_simple_molecule_cytoplasm | (angiotensin_A_simple_molecule & sa30_ACE2_cytoplasm)) $aldosterone_simple_molecule: sa204_AGTR1_cytoplasm $angiotensin_1_4_simple_molecule: (angiotensin_1_12_simple_molecule & sa39_MME_cytoplasm) $angiotensin_1_5_simple_molecule: (angiotensin_1_7_simple_molecule_cytoplasm & sa100_ACE_cytoplasm) $angiotensin_1_7_simple_molecule_cytoplasm: (((((((sa100_ACE_cytoplasm | sa39_MME_cytoplasm) & angiotensin_1_9_simple_molecule) | ((sa30_ACE2_cytoplasm | PRCP) & angiotensin_II_simple_molecule_cytoplasm)) | (angiotensin_I_simple_molecule & sa39_MME_cytoplasm)) | (angiotensin_1_12_simple_molecule & sa39_MME_cytoplasm)) | (angiotensin_I_simple_molecule & THOP1)) | (angiotensin_I_simple_molecule & PREP)) $angiotensin_1_7_simple_molecule_default_compartment: (angiotensin_II_simple_molecule_default_compartment & ACE2__soluble) $angiotensin_1_9_simple_molecule: (angiotensin_I_simple_molecule & sa30_ACE2_cytoplasm) $angiotensin_3_7_simple_molecule: ((angiotensin_1_7_simple_molecule_cytoplasm | angiotensin_II_simple_molecule_cytoplasm) | angiotensin_IV_simple_molecule) $angiotensin_A_simple_molecule: angiotensin_II_simple_molecule_cytoplasm $angiotensin_III_simple_molecule: (angiotensin_II_simple_molecule_cytoplasm & sa64_ENPEP_cytoplasm) $angiotensin_II_simple_molecule_cytoplasm: (((((angiotensin_I_simple_molecule & sa29_ACE_cytoplasm) | S) | (angiotensin_1_12_simple_molecule & CMA1)) | (angiotensin_I_simple_molecule & CMA1)) | (angiotensin_I_simple_molecule & KLK1)) $angiotensin_II_simple_molecule_default_compartment: SARS_CoV_2_infection_phenotype $angiotensin_IV_simple_molecule: (angiotensin_III_simple_molecule & ANPEP_) $angiotensin_I_simple_molecule: (((AGT & REN) | (angiotensin_1_12_simple_molecule & sa29_ACE_cytoplasm)) | ((CTSD | CTSG) & AGT)) $cognition_phenotype: (sa102_AGTR1_cytoplasm | sa156_LNPEP_cytoplasm) $fibrosis_phenotype: ((sa27_MAS1_cytoplasm | sa25_AGTR2_cytoplasm) | sa102_AGTR1_cytoplasm) $inflammatory_response_phenotype: (((sa50_MRGPRD_cytoplasm | sa27_MAS1_cytoplasm) | sa156_LNPEP_cytoplasm) | sa102_AGTR1_cytoplasm) $neurodegeneration_phenotype: sa156_LNPEP_cytoplasm $oxidative_stress_phenotype: (sa27_MAS1_cytoplasm | sa102_AGTR1_cytoplasm) $platelet_aggregation_phenotype: sa102_AGTR1_cytoplasm $pulmonary_edema_phenotype: sa102_AGTR1_cytoplasm $sa100_ACE_cytoplasm: ((((sa28_ACE_cytoplasm & !aging_phenotype) & !sa44_sex__male_phenotype_default_compartment) | (sa28_ACE_cytoplasm & aldosterone_simple_molecule)) | (sa28_ACE_cytoplasm & hypertension_phenotype)) $sa102_AGTR1_cytoplasm: (((((angiotensin_II_simple_molecule_cytoplasm | angiotensin_IV_simple_molecule) | angiotensin_A_simple_molecule) & sa26_AGTR1_cytoplasm) | (sa26_AGTR1_cytoplasm & !Losartan_drug)) | (sa26_AGTR1_cytoplasm & !angiotensin_1_7_simple_molecule_cytoplasm)) $sa140_AGTR1_cytoplasm: (angiotensin_II_simple_molecule_cytoplasm & !MAS1_AGTR1_complex) $sa146_ACE_cytoplasm: ((sa29_ACE_cytoplasm & !Lisinopril_drug) | (sa29_ACE_cytoplasm & ABO_blood_group_system_phenotype)) $sa156_LNPEP_cytoplasm: ((sa152_LNPEP_cytoplasm & angiotensin_IV_simple_molecule) | (sa152_LNPEP_cytoplasm & angiotensin_3_7_simple_molecule)) $sa194_MME_cytoplasm: (sa39_MME_cytoplasm & sa44_sex__male_phenotype_default_compartment) $sa25_AGTR2_cytoplasm: ((((sa79_AGTR2_cytoplasm & CGP42112A_drug) | ((angiotensin_II_simple_molecule_cytoplasm | angiotensin_A_simple_molecule) & sa79_AGTR2_cytoplasm)) | (sa79_AGTR2_cytoplasm & angiotensin_1_7_simple_molecule_cytoplasm)) | (sa79_AGTR2_cytoplasm & angiotensin_1_9_simple_molecule)) $sa27_MAS1_cytoplasm: (((sa77_MAS1_cytoplasm & angiotensin_1_5_simple_molecule) | (sa77_MAS1_cytoplasm & AR234960_drug)) | (sa77_MAS1_cytoplasm & angiotensin_1_7_simple_molecule_cytoplasm)) $sa29_ACE_cytoplasm: (sa200_estradiol_simple_molecule_cytoplasm & !Calcitriol_simple_molecule_cell) $sa30_ACE2_cytoplasm: ((((((sa169_estradiol_simple_molecule_cytoplasm | Calcitriol_simple_molecule_cytoplasm) & ACE2_gene) & !S) | !SARS_CoV_2_infection_phenotype) | (ACE2_gene & aging_phenotype)) | ((ACE2_gene & !hypertension_phenotype) & !_Diabetes_mellitus__type_II_phenotype)) $sa50_MRGPRD_cytoplasm: ((sa94_MRGPRD_cytoplasm & alamandine_simple_molecule) | (sa94_MRGPRD_cytoplasm & angiotensin_1_7_simple_molecule_cytoplasm)) $sa64_ENPEP_cytoplasm: ((sa162_ENPEP_cytoplasm & !QGC001_drug) | (sa162_ENPEP_cytoplasm & !sa193_sex__male_phenotype_default_compartment)) $sa77_MAS1_cytoplasm: !aldosterone_simple_molecule $sa98_ACE2_cytoplasm: ((sa30_ACE2_cytoplasm & sa44_sex__male_phenotype_default_compartment) | ((aging_phenotype | hypertension_phenotype) & sa30_ACE2_cytoplasm)) $thrombosis_phenotype: (sa27_MAS1_cytoplasm | sa102_AGTR1_cytoplasm) $vasoconstriction_phenotype: ((((sa25_AGTR2_cytoplasm | sa27_MAS1_cytoplasm) | sa156_LNPEP_cytoplasm) | sa50_MRGPRD_cytoplasm) | sa102_AGTR1_cytoplasm) $viral_replication_cycle_phenotype: ACE2_Spike_complex_complex